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BOOK SUMMARY :

Background recent studies have shown that disruption of circadian rhythms is one of the tumor promoting factors which contribute to mammalian cancer development and progression but very little is known about the molecular changes of circadian genes in colorectal carcinoma crcnote citations are based on reference standards however formatting rules can vary widely between applications and fields of interest or study the specific requirements or preferences of your reviewing publisher classroom teacher institution or organization should be applieddr peter tothy is an oncologist in crown point indiana and is affiliated with multiple hospitals in the area including community hospital munster and franciscan health crown pointhe received evidence from population based in vivo and in vitro studies have implicated circadian rhythms in the control of cancer and are consistent with the hypothesis that specific components in the host circadian timing system regulate tumor growth factors regulating tumor growth share the capacity to modulate peripheral clocks the cell cycle and energy metabolism circadian variation in drug metabolism and tissue sensitivity to drugs affects their activity and toxicity a growing body of data suggests that therapy may be improved and toxicity reduced by

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